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MENOPAUSE & HORMONE THERAPY

Be Yourself Again.

Bioidentical hormone therapy for the menopause transition, selected and dosed by a licensed provider. Patch, gel, tablet, cream, or compounded Biest.

From $85/mo. Every price shown below.

PROVIDER REVIEW IN 24-48H · SHIPS IN DAYS

Rx programs require an online visit with a licensed provider · results vary.

HER STORY · THROUGH MENOPAUSE

The run that never stops.

A mother and daughter on their morning run. Seasons change, the daughter grows, and the mother never stops. Not through the years, and not through menopause. With provider-guided hormone care, she keeps showing up: same trail, same daughter, year after year.

EVERY OPTION · EVERY PRICE

The transition is real. So is the support.

Hot flashes, broken sleep, brain fog, mood shifts. Menopause is a genuine hormonal change, not something to push through. One online visit covers every format below; your provider selects the route and dose with you.

Biest 50:50
Biest 50:50
$120/mo
TOPICAL · NEEDLE-FREE

Why it's used: a compounded blend of two bioidentical estrogens (estradiol + estriol), prescribed during the menopause transition when a provider determines estrogen support is appropriate.

  • Supports comfort through hot flashes and night sweats
  • Supports more restful, less interrupted sleep
  • Supports vaginal and genitourinary comfort
  • Supports a steadier mood through the transition
  • Supports bone health as natural estrogen declines
  • Supports skin and tissue elasticity
POSSIBLE SIDE EFFECTS
  • Breast tenderness, bloating, nausea, or headache
  • Spotting or vaginal bleeding
  • Estrogen therapy carries an increased risk of blood clots and stroke; review your history with your provider
  • Compounded formulations are not FDA-approved or standardized

Talk to your provider before starting or changing any treatment.

Biest 50:50 + Progesterone
Biest 50:50 + Progesterone
$120/mo
TOPICAL + ORAL · NEEDLE-FREE

Why it's used: Biest paired with oral micronized progesterone, which protects the uterine lining when estrogen is used by a woman with a uterus.

  • Supports comfort through hot flashes and night sweats
  • Supports the uterine lining while estrogen is in use
  • Supports sleep when progesterone is taken at bedtime
  • Supports a steadier mood through the transition
  • Supports bone health as natural estrogen declines
  • Supports a balanced, provider-monitored hormone routine
POSSIBLE SIDE EFFECTS
  • Breast tenderness, bloating, mood changes, or headache
  • Progesterone can cause drowsiness or dizziness; dose at bedtime
  • Estrogen therapy carries an increased risk of blood clots and stroke
  • Compounded formulations are not FDA-approved or standardized

Talk to your provider before starting or changing any treatment.

Estradiol Gel
Estradiol Gel
$140/mo · $270/quarter
TOPICAL · NEEDLE-FREE

Why it's used: a transdermal bioidentical estradiol gel applied to the skin daily, chosen when a provider prefers a through-the-skin route.

  • Supports comfort through hot flashes and night sweats
  • Supports vaginal and genitourinary comfort
  • Supports more restful sleep
  • Supports bone health as natural estrogen declines
  • Supports steady day-to-day dosing in a simple routine
  • Through-the-skin delivery avoids first-pass processing by the liver
POSSIBLE SIDE EFFECTS
  • Breast tenderness, headache, nausea, or bloating
  • Skin irritation where applied; let it dry before skin contact with others
  • Estrogen therapy carries an increased risk of blood clots and stroke, and of endometrial changes if unopposed; your provider will pair it appropriately

Talk to your provider before starting or changing any treatment.

Estradiol Patch
Estradiol Patch
$140/mo · $275/quarter
TOPICAL PATCH · NEEDLE-FREE

Why it's used: a wear-and-forget transdermal estradiol patch, replaced on a set schedule for steady delivery.

  • Supports comfort through hot flashes and night sweats
  • Supports steady, consistent delivery between changes
  • Supports vaginal and genitourinary comfort
  • Supports more restful sleep
  • Supports bone health as natural estrogen declines
  • Through-the-skin delivery avoids first-pass processing by the liver
POSSIBLE SIDE EFFECTS
  • Breast tenderness, headache, nausea, or bloating
  • Skin irritation at the patch site; patches can loosen with heat or sweat
  • Estrogen therapy carries an increased risk of blood clots and stroke, and of endometrial changes if unopposed

Talk to your provider before starting or changing any treatment.

Estradiol Tablet
Estradiol Tablet
$85/mo · $90/quarter
ORAL

Why it's used: a once-daily oral bioidentical estradiol tablet. The simplest routine at the most accessible price.

  • Supports comfort through hot flashes and night sweats
  • Supports vaginal and genitourinary comfort
  • Supports more restful sleep
  • Supports bone health as natural estrogen declines
  • Supports a simple once-daily routine
  • Supports an accessible starting point your provider can adjust
POSSIBLE SIDE EFFECTS
  • Breast tenderness, headache, nausea, or bloating
  • Oral estrogen carries a higher clot and stroke risk than through-the-skin routes; discuss your history
  • Endometrial changes if unopposed by progesterone; vaginal bleeding

Talk to your provider before starting or changing any treatment.

Estradiol Vaginal Cream
Estradiol Vaginal Cream
$115/mo
LOCAL · NEEDLE-FREE

Why it's used: a low-dose estradiol cream applied locally for the vaginal and urinary symptoms of menopause.

  • Supports vaginal moisture and elasticity
  • Supports comfort during intimacy
  • Supports urinary comfort
  • Supports local tissue health with minimal systemic absorption at low dose
  • Supports women whose main symptoms are genitourinary
  • Supports use alongside other therapies your provider selects
POSSIBLE SIDE EFFECTS
  • Local irritation, itching, or discharge
  • Some systemic absorption is possible; breast tenderness or spotting
  • Long-term use without progesterone may carry endometrial risk in women with a uterus

Talk to your provider before starting or changing any treatment.

Progesterone Capsules
Progesterone Capsules
$95/mo
ORAL

Why it's used: oral micronized progesterone, taken at bedtime, on its own or paired with estrogen to protect the uterine lining.

  • Supports the uterine lining during estrogen therapy
  • Supports sleep when taken at bedtime
  • Supports hormone balance through the transition
  • Supports cycle regulation in perimenopause
  • Supports a calm evening wind-down routine
  • Supports pairing with any estrogen format your provider selects
POSSIBLE SIDE EFFECTS
  • Drowsiness, dizziness, or fatigue; take at bedtime
  • Breast tenderness, bloating, or mood changes
  • Headache; caution with peanut allergy in some oil-based formulations

Talk to your provider before starting or changing any treatment.

Delivery Routes, Explained

Different routes fit different bodies and different lives. Your provider selects the route with you. This is a qualitative guide, not a ranking. Menopause care at HOO is entirely needle-free.

Oral

Swallowed as a capsule or tablet and absorbed through the digestive tract. The simplest routine of all.

Topical

Applied to the skin, working where you apply it, with gradual absorption. Creams, gels, patches, and solutions.

Route differences are described qualitatively; we don't publish absorption percentages because well-controlled comparative human data are limited. For the peer-reviewed research behind each molecule class, see our science library. Rx programs require an online visit with a licensed provider · results vary.